Setbacks in Alzheimer research demand new strategies, not surrender

نویسندگان

  • Björn Jobke
  • Thomas McBride
  • Linda Nevin
  • Larry Peiperl
  • Amy Ross
  • Clare Stone
  • Richard Turner
چکیده

In this month's editorial, the PLOS Medicine Editors discuss the challenges of addressing a growing population with Alzheimer disease and dementia amidst disappointing news from the pharmaceutical industry.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Early Default Risk and Surrender Risk: Impacts on Participating Life Insurance Policies

We study the fair valuation of participating life insurance policies with surrender guarantees when an early default mechanism is imposed by a regulator. An insurance company is forced to be liquidated once a solvency threshold is reached before maturity. The early default regulation affects the contracts’ value not only directly via changing the contracts’ payment streams but also indirectly v...

متن کامل

Risk Management of Policyholder Behavior in Equity-Linked Life Insurance

The financial guarantees embedded in variable annuity (VA) contracts expose insurers to a wide range of risks, lapse risk being one of them. When policyholders’ lapse behavior differs from the assumptions used to hedge VA contracts, the effectiveness of dynamic hedging strategies can be significantly impaired. By studying how the fee structure and surrender charges affect surrender incentives, ...

متن کامل

Effect of problem-oriented coping strategies training on perceived stress in the family caregivers of the elderly with Alzheimer

Background & Aim: The caregivers of Alzheimer's patients frequently experience more psychological illness, depression, stress, and discomfort than their peers who do not care for Alzheimer's patients or care for physically ill patients. The aim of this study was to determine the effect of problem-oriented coping strategies training on perceived stress in the family caregivers of the elderly wit...

متن کامل

Optimal Surrender Strategies for Equity-Indexed Annuity Investors

An equity-indexed annuity (EIA) is a hybrid between a variable and a fixed annuity that allows the investor to participate in the stock market and earn at least a minimum interest rate. The investor sacrifices some of the upside potential for the downside protection of the minimum guarantee. Because EIAs allow investors to participate in equity growth without the downside risk, their popularity...

متن کامل

Increasing ethnic minority participation in Alzheimer disease research.

The Alzheimer's Association and National Institutes of Health have emphasized the need for participation of racial/ethnic populations in Alzheimer disease (AD) clinical research. Many articles have described strategies to enhance participation including establishing enduring ties to the community and tailoring the site to be more culturally welcoming or user-friendly to the community. Yet, most...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 15  شماره 

صفحات  -

تاریخ انتشار 2018